Dimethyl-SGD-1882 Size:Contact [email protected] for quotation 2R)-1-hydroxy-1-phenylpropan-2-yl]carbamoyl}-1-methoxy-2-methylethyl]pyrrolidin-1-yl]-3-methoxy-5-methyl-1-oxoheptan-4-yl](methyl)carbamoyl}-2-methylpropyl]carbamoyl}-2-methylpropyl]-N-methylhexanamide

2R)-1-hydroxy-1-phenylpropan-2-yl]carbamoyl}-1-methoxy-2-methylethyl]pyrrolidin-1-yl]-3-methoxy-5-methyl-1-oxoheptan-4-yl](methyl)carbamoyl}-2-methylpropyl]carbamoyl}-2-methylpropyl]-N-methylhexanamide

Smiles: OC1C=CC=C(CNC(=O)NC2=NC(=CS2)C2C=CN=CC=2)C=1

4(7):873-83

36 nM respectively

SirReal2 can increase tubulin hyperacetylation in HeLa cells and induces destabilization of the checkpoint protein BubR1

Dimethyl-SGD-1882 Size:Contact [email protected] for quotation 2R)-1-hydroxy-1-phenylpropan-2-yl]carbamoyl}-1-methoxy-2-methylethyl]pyrrolidin-1-yl]-3-methoxy-5-methyl-1-oxoheptan-4-yl](methyl)carbamoyl}-2-methylpropyl]carbamoyl}-2-methylpropyl]-N-methylhexanamideDimethyl SGD 1882 (Dimethyl PBD dimer) is a highly potent DNA alkylator, and is used as an antibody drug conjugate (ADC) cytotoxin. PBD Dimer is a DNA alkylator which inhibits DNA replication. Product information Molecular Weight: 753. 84 Formula: C44H43N5O7 Chemical Name: (6aR) 3 [3 [[(6aR) 2 methoxy 8 (4 methoxyphenyl) 6a methyl 11 oxo 7H pyrrolo[2, 1 c][1, 4]benzodiazepin 3 yl]oxy]propoxy] 8 (4 aminophenyl) 2 methoxy 6a methyl 7H pyrrolo[2, 1 c][1,