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Cinobufotalin Catalog No.:M8397-10 3-[(2-methylphenyl)methylsulfanyl]-6-pyridin-2-ylpyridazine

SKU: 60294735333

4.7
USD138.00 USD170.00

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Description

3-[(2-methylphenyl)methylsulfanyl]-6-pyridin-2-ylpyridazine

SQ-11725 D9

NVP-LXS196

Solubility: DMSO: 50 mg/mL (ultrasonic

57Dihydroxyflavone

Cinobufotalin Catalog No.:M8397-10 3-[(2-methylphenyl)methylsulfanyl]-6-pyridin-2-ylpyridazineCinobufotalin is a steroid glycoside that reduces SRC 3 protein levels in MCF 7 breast cancer cells, Na+ K+ pump activity, viability, and cell attachment of C7 MDCK cells, and expression of the epithelial mesenchymal (EMT) markers E cadherin, vimentin, ZEB1, and Slug in. Cinobufotalin is cytotoxic to A549, H460, and HTB 58 lung cancer cells. In vivo, Cinobufotalin reduces tumor volume and increases survival in an A549 mouse xenograft model. Product

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