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Chemical Name: tert-butyl (4-(3-((7-(hydroxyamino)-7-oxoheptyl)carbamoyl)isoxazol-5-yl)phenyl)carbamate
and thereby suppresses the growth of synovial sarcoma cells
43 mM) Ethanol 6 mg/mL (19
CAS Number: 1233948-35-0
with an IC50 value of 13 nM
GDC-0879 - CAS# 905281-76-7 Size:10mg solid Chemical Name: tert-butyl (4-(3-((7-(hydroxyamino)-7-oxoheptyl)carbamoyl)isoxazol-5-yl)phenyl)carbamateGDC 0879 is a highly selective, potent, and orally bioavailable RAF small molecule inhibitor. In GDC 0879 treated mice, both cell line and patient derived BRAF(V600E) tumors exhibited stronger and more sustained pharmacodynamic inhibition (>90% for 8 hours) and improved survival compared with mutant KRAS expressing tumors. Product information CAS Number: 905281 76 7 Molecular Weight: 334. 37 Formula: C19H18N4O2 Synonym: GDC0879 GDC 0879 Chemical Name:
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