SR1078 - CAS# 1246525-60-9 acapone Also inhibits other common kinases

Also inhibits other common kinases including EGFR (IC50 = 4 nM)

Smiles: [Sr+2]

Neuronal cultures treated with other toxic stimuli such as staurosporine

Vistide dihydrate

Aleuritic acid derivates have Anti-HIV activity

SR1078 - CAS# 1246525-60-9 acapone Also inhibits other common kinasesSR 1078 is a selective agonist of ROR and ROR that stimulates ROR transcriptional activity in HEK293 cell reporter assays at concentrations as low as 2 M without effect at the related liver X receptors and farnesoid X receptors. SR1078 modulates the conformation of ROR in a biochemical assay and activates ROR and ROR driven transcription. SR1078 stimulates expression of endogenous ROR target genes in HepG2 cells that express both ROR and ROR. SR1078