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incorporates an E3 ligase ligand plus an alkylC9 linker with terminal carboxylic acid ready for conjugation to a target protein ligand
QTX125 has antitumor effects
every 3 rd day
Formula: C7H12O3
11a-tetramethyl-7
Dicoumarol 2523 incorporates an E3 ligase ligandDicoumarol is an inhibitor of both NAD(P)H: quinone oxidoreductase 1 (NQO1) and PDK1 with IC50s of 0. 37 and 19. 42 M, respectively. Product information CAS Number: 66 76 2 Molecular Weight: 336. 29 Formula: C19H12O6 Chemical Name: 4 hydroxy 3 [(4 hydroxy 2 oxo 2H chromen 3 yl)methyl] 2H chromen 2 one Smiles: OC1=C(CC2C(=O)OC3=CC=CC=C3C=2O)C(=O)OC2=CC=CC=C12 InChiKey: DOBMPNYZJYQDGZ UHFFFAOYSA N InChi: InChI=1S C19H12O6 c20 16 10 5 1 3 7 14(10)24
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