![TAE-1 ethylbenzenesulfonate 3-benzodioxol-5-yl)acetyl]thiophene-3-sulfonamide](https://cdn.shopify.com/s/files/1/0389/1897/9723/files/1685413122751.png?v=1685413146)
Pay in 4 interest-free payments of $25.00 Learn more
Ships within 48 hours · Estimated delivery Aug 2 - Aug 7
3-benzodioxol-5-yl)acetyl]thiophene-3-sulfonamide
InChi: InChI=1S/C22H25N7O2/c1-29-11-13(9-25-29)20-16-10-24-28-21(30)15-7-14(8-17(27-20)18(15)16)26-22(31)19(23)12-5-3-2-4-6-12/h7-12
17)18)13(21)11-6-3-7-23-11/h2-8
Smiles: CCCC1=CC(=CC=N1)C1=NC(=CS1)C1C=CC(=CC=1)NS(C)(=O)=O
3389/fphar
TAE-1 ethylbenzenesulfonate 3-benzodioxol-5-yl)acetyl]thiophene-3-sulfonamideIC50: 0. 3 0. 02 M for AChE; 3. 9 0. 2 M for BuChE TAE 1 is an inhibitor of amyloid fibril formation and aggregation. Alzheimers disease (AD), a progressive neurodegenerative disorder, is characterized by the cerebral accumulation of insoluble aggregates of amyloid peptides (A). Although the precise mechanisms governing neuronal loss remains ambiguous, toxicity resulting from A activated pathways is evident. In vitro: In a previous study, the authors