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Sortin1 is a sorting inhibitor
Myocardial remodeling in diabetic cardiomyopathy associated with cardiac mast cell activation
InChi: InChI=1S/C21H18O5/c22-20-9-8-16-19(26-20)14-18-17(10-13-24-18)21(16)25-12-5-4-11-23-15-6-2-1-3-7-15/h1-3
CAS Number: 882257-11-6
OTS514 exhibits growth suppressive effect on small cell lung cancer
BI-D1870 - CAS# 501437-28-1 Catalog No.:M11147-2 Sortin1 is a sorting inhibitorBI D1870 is a potent and specific RSK inhibitor (the p90 ribosomal S6 kinase), which inhibits RSK1, RSK2, RSK3 and RSK4 in vitro with an IC50 of 1030 nM. BI D1870 exhibited a dose responsive antiproliferative effect on OSCC cells with relative sparing of normal human oral keratinocytes. The compound inhibited the downstream RSK target YB 1 and caused apoptosis. In addition, BI D1870 also induced G2 M arrest by modulating the expression of p21 and
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