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GSK3368715 dihydrochloride 14893 CAS Number: 175865-59-5

SKU: 17445815800

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Description

CAS Number: 175865-59-5

InChiKey: NGGGSSRQKFKPSX-XQBPLPMBSA-N

AT-7519 trifluoroacetate

InChi: InChI=1S/C29H48O/c1-7-21(19(2)3)9-8-20(4)25-12-13-26-24-11-10-22-18-23(30)14-16-28(22

InChiKey: KPURUIUXBWTRPB-UHFFFAOYSA-N

GSK3368715 dihydrochloride 14893 CAS Number: 175865-59-5GSK3368715 dihydrochloride (EPZ019997 dihydrochloride) is an orally active, reversible, and S adenosyl L methionine (SAM) uncompetitive type I protein arginine methyltransferases (PRMTs) inhibitor (IC50=3. 1 nM (PRMT1), 48 nM (PRMT3), 1148 nM (PRMT4), 5. 7 nM (PRMT6), 1. 7 nM (PRMT8)). GSK3368715 dihydrochloride (EPZ019997 dihydrochloride) produces a shift in arginine methylation states, alters exon usage, and has strong anti cancer activity. Product

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