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3Na/c11-8-3-6(21(12
CX-4945 exhibits a broad spectrum of antiproliferative activity
PDGFRβ and Flt4 with IC50 of 14 nM
specifically in mutant p53-expressing colorectal cancer cells
Solubility: DMSO up to 10 mM
PROTAC SGK3 degrader-1 Size:2mg solid 3Na/c11-8-3-6(21(12PROTAC SGK3 degrader 1 (SGK3 PROTAC1), is a potent SKG3 degrader based on PROTAC. PROTAC SGK3 degrader 1 (0. 3 M) induces 50% degradation of endogenous SGK3 within 2 hours, with maximal 80% degradation observed within 8 hours, accompanied by a loss of phosphorylation of NDRG1 (an SGK3 substrate). Product information CAS Number: 2381320 35 8 Molecular Weight: 1157. 38 Formula: C57H73FN10O11S2 Chemical Name: (2S, 4R) 1 [(2S) 2 (2 {2 [2 ({6 [(2R) 2 [({6
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