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PubMed PMID: 22001744
(2008) Nat Biotechnol
ACY-1215 (Rocilinostat)
PMCID: PMC6063991
including all members of the AKT family that had not been previously detected by other broad-spectrum kinase inhibitors
Entrectinib - CAS# 1108743-60-7 size:10mg solid PubMed PMID: 22001744Entrectinib, CAS No. 1108743 60 7, also known as RXDX 101 and NMS E628, is an oral small molecule inhibitor of TrkA, TrkB and TrkC, as well as ROS1 and ALK, with high potency and selectivity. RXDX 101 has demonstrated potent pharmacological activity in preclinical studies and has the potential to be first in class against the Trk family of kinases. PXDX 101 has been well tolerated in patients with advanced solid tumors. PXDX 101 is currently in