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Translational pharmacology of an inhaled small molecule αvβ6 integrin inhibitor for idiopathic pulmonary fibrosis
Selective small-molecule inhibition of an RNA structural element
Alternative cultures for human pluripotent stem cell production
CAS Number: 380843-75-4
IV-361 exhibits excellent HCT-116 cell growth inhibitory activity (GI50≤100 nM)
Giredestrant Catalog No.:M27166-C Translational pharmacology of an inhaledGiredestrant (GDC 9545), a non steroidal estrogen receptor (ER) ligand, is an orally active and selective ER antagonist. Giredestrant potently competes with Estradiol for binding and induces a conformational change within the ER ligand binding domain. Giredestrant has anti tumor activity. Product information CAS Number: 1953133 47 5 Molecular Weight: 522. 55 Formula: C27H31F5N4O Chemical Name: 3 [(1R,3R) 1 (2,6 difluoro 4 {[1 (3 fluoropropyl)azetidin
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