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Formula: C17H20N2O3
InChiKey: YDIKCZBMBPOGFT-PWUSVEHZSA-N
Molecular Weight: 707
Smiles: CN(C)C1=CC(=CC=C1)C1=C2C(=CC(=O)N1C)NN(C1=CC=CC=C1Cl)C2=O
InChi: InChI=1S/C15H20ClN3O2/c1-14(2
NNGH - CAS# 161314-17-6 798CG-100602 Formula: C17H20N2O3Ki: 9, 2. 6, 4. 3, 3. 1, and 17 nM for MMP 8, 9, 12, 13, and 20, respectively. NNGH is an inhibitor of MMPs. Matrix metalloproteinases (MMPs), a large class of strictly related zincdependent enzymes, belong to the family of proteolytic enzymes. MMPs are involved in various aspects of physiological cellular processes and pathologies, such as pulmonary emphysema, reumathoid arthritis, tumor growth and metastasis. In vitro: Previous study found that NNGH