Novel potent and selective inhibitors of p90 ribosomal S6 kinase reveal the heterogeneity of RSK function in MAPK-driven cancers
InChi: InChI=1S/C26H22N2O2/c1-18(19-9-3-2-4-10-19)28-26(30)22-13-7-8-14-24(22)27-17-23-21-12-6-5-11-20(21)15-16-25(23)29/h2-18
as a selective Pkc1 kinase inhibitor through high-throughput screening
There are currently no effective therapies for fibrodysplasia ossificans progressiva (FOP)
InChiKey: QRMALYUMKBOEGR-KXLOKULZSA-N
NS-102 071ethyl 3-aminopropanoate hydrochloride Novel potent and selective inhibitorsNS 102 is a selective kainate (GluK2) receptor antagonist. NS 102 is a potent GluR6 7 receptor antagonist. Product information CAS Number: 136623 01 3 Molecular Weight: 261. 23 Formula: C12H11N3O4 Chemical Name: 5 nitro 3 nitroso 1H,6H,7H,8H,9H cyclohexa[g]indol 2 ol Smiles: [O ][N+](=O)C1=CC2=C(NC(O)=C2N=O)C2CCCCC=21 InChiKey: SADZJARZJNQZHT UHFFFAOYSA N InChi: InChI=1S C12H11N3O4 c16 12 11(14 17)8 5 9(15(18)19)6 3 1 2 4 7(6)10(8)13 12 h5,13,16H,1