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K777 Catalog No.:M33083-C the expression level of GRM4

SKU: 29352161602

4.6
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Description

the expression level of GRM4 in the hippocampus is reliable down-regulated five days after treatment with TCN 238

5-a]pyrimidin-7-ylamino)cyclopentyl)methyl sulfamate

InChiKey: DUNMULOWUUIQIL-RGMNGODLSA-N

InChi: InChI=1S/C27H28BrNO3/c1-19-22(10-7-11-23(19)21-8-3-2-4-9-21)18-32-26-14-13-20(16-24(26)28)17-29-15-6-5-12-25(29)27(30)31/h2-4

InChiKey: UCAFJBSQKXVPDX-UHFFFAOYSA-N

K777 Catalog No.:M33083-C the expression level of GRM4K777 is a potent, orally active and irreversible cysteine protease inhibitor. K777 is also a potent CYP3A4 inhibitor with an IC50 of 60 nM and a selective CCR4 antagonist featuring the potent chemotaxis inhibition. K777 irreversibly inhibits Cruzain, the major cysteine protease of Trypansoma cruzi, and cathepsins B and L. K777 is a broad spectrum antiviral by targeting cathepsin mediated cell entry. K777 inhibits SARS CoV and EBOV pseudovirus entry

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