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BI-3663 (cereblon-based) degrades focal adhesion tyrosine kinase (PTK2) with a median DC50 of 30 nM to >80% across a panel of 11 human hepatocellular carcinoma (HCC) cell lines
InChiKey: QSKQVZWVLOIIEV-NSHDSACASA-N
CAS Number: 668270-12-0
It is also a specific inhibitor of Ubiquitin E3 ligase
InChiKey: YTINZZFBHWSAGL-NDEPHWFRSA-N
Rosuvastatin D6 Calcium florasone diacetate BI-3663 (cereblon-based) degrades focal adhesionRosuvastatin D6 Calcium is deuterium labeled Rosuvastatin, which is a competitive inhibitor of HMG CoA reductase with IC50 of 11 nM. Product information Molecular Weight: 506. 61 Formula: C44H54CaF2N6O12S2 Chemical Name: calcium bis((3R,5S,6E) 7 [4 (4 fluorophenyl) 2 (N methylmethanesulfonamido) 6 [(1,1,1,3,3,3 H)propan 2 yl]pyrimidin 5 yl] 3,5 dihydroxyhept 6 enoate) Smiles: [Ca+2].[2H]C([2H])([2H])C(C1=NC(=NC(=C1 C=C [C@@H](O)C[C@@H](O)CC([O
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