alpha-1 antitrypsin fragment Catalog No.:M23456-C Synthesis and structure-activity relationship studies

Synthesis and structure-activity relationship studies of conformationally flexibletetrahydroisoquinolinyl triazole carboxamide and triazole substituted benzamide analogues as σ2 receptor ligands

Smiles: CC(=O)O[C@@H]1[C@H](C2C=CC(=O)OC=2)[C@@]2(C)CC[C@H]3[C@@H](CC[C@@H]4C[C@@H](O)CC[C@@]43C)[C@@]32O[C@@H]31

but not the tumor cells B16F1

InChi: InChI=1S/C15H12O2/c16-13-10-15(11-6-2-1-3-7-11)17-14-9-5-4-8-12(13)14/h1-9

CAS Number: 41137-87-5

alpha-1 antitrypsin fragment Catalog No.:M23456-C Synthesis and structure-activity relationship studiesAlpha 1 antitrypsin (A1AT) (H2N Leu Gln His Leu Glu Asn Glu Leu Thr His Asp Ile Ile Thr Lys OH), which is known as serum trypsin inhibitor, is a protease inhibitor belonging to the serpin superfamily. A1AT is a single chain glycoprotein consisting of 394 amino acids in the mature form and exhibits a number of glycoforms. The three N linked glycosylations sites are mainly equipped with so called diantennary N glycans. However, one particular site shows