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K858 Racemic is an ATP-uncompetitive inhibitor of Eg5 with an IC50 of 1
At doses of 5
Smiles: C[C@]12CC[C@H]3[C@@H](CC[C@@H]4C[C@@H](O)CC[C@@]43C)[C@@]1(O)CC[C@]2(O)C1C=COC=1
CAS Number: 14197-60-5
479347-85-8
Calcipotriol - CAS# 112965-21-6 0591 K858 Racemic is an ATP-uncompetitiveCalcipotriol, a synthetic derivative of calcitriol or Vitamin D, is used in the treatment of psoriasis and marketed under the trade name Dovonex. It has comparable affinity with calcitriol (Vit. D) for the Vitamin D receptor (VDR), while being less than 1% as active as the calcitriol in regulating calcium metabolism. Chronic plaque psoriasis is the chief medical use of calcipotriol. It has also been used successfully in the treatment of alopecia
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