PKC-IN-1 - CAS# 1046787-18-1 size:10mg solid NVP-ACC789 also completely inhibits VEGF-induced

NVP-ACC789 also completely inhibits VEGF-induced BME and BAE cell invasion and VEGF-C-induced BAE cell invasion

(2009) Cell Stem Cell

1781828-85-0

Ionomycin is a Calcium ionophore and an antibiotic produced by Streptomyces conglobatus

US 20090325960 A1

PKC-IN-1 - CAS# 1046787-18-1 size:10mg solid NVP-ACC789 also completely inhibits VEGF-inducedPKC IN 1, CAS No. 1046787 18 1, is a potent, ATP competitive and reversible inhibitor of conventional PKC enzymes with Kis of 5. 3 and 10. 4 nM for human PKC and PKC, and IC50s of 2. 3, 8. 1, 7. 6, 25. 6, 57. 5, 314, 808 nM for PKC, PKCI, PKCII, PKC, PKC, PKC mu and PKC, respectively. IC50: 2. 3 nM (Human PKC), 7. 6 nM (Human PKCII), 8. 1 nM (Human PKCI), 25. 6 nM (Human PKC), 57. 5 nM (Human PKC), 314 nM (Human PKC mu), 808 nM (Human PKC) Ki: 5. 3 nM