Pay in 4 interest-free payments of $11.25 Learn more
Ships within 48 hours · Estimated delivery Aug 6 - Aug 11
Mefentrifluconazole is not a skin or an eye irritant
It causes cell death through the apoptosis pathway
PubMed PMID: 26675256
Makiyama A
InChi: InChI=1S/C26H28F3N7O2/c1-33-10-12-35(13-11-33)17-8-9-19(22(14-17)38-3)31-25-30-15-21-23(32-25)34(2)20-7-5-4-6-18(20)24(37)36(21)16-26(27
Selonsertib free base - CAS# 1448428-04-3 0321 Mefentrifluconazole is not a skinSelonsertib free base, CAS No. 1448428 04 3, also known as GS 4997, is an orally bioavailable inhibitor of apoptosis signal regulating kinase 1 (ASK1), with potential anti inflammatory, antineoplastic and anti fibrotic activities. GS 4997 targets and binds to the catalytic kinase domain of ASK1 in an ATP competitive manner, thereby preventing its phosphorylation and activation. GS 4997 prevents the production of inflammatory cytokines, down regulates