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8 μM for inhibition of human recombinant CCR2b and CCR1 receptors respectively)
and converted from acetoacetic acid catalyzed by 3-hydroxybutyrate dehydrogenase
InChi: InChI=1S/C19H19ClN6O2/c1-11(22-19(28)18-8-17(12(2)27)23-24-18)10-26-6-5-16(25-26)13-3-4-14(9-21)15(20)7-13/h3-8
α-Cyano-4-hydroxycinnamic acid is used as a matrix to facilitate peptide ionization in matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry applications
22 mg/mL (42
MT1 6727 8 μM for inhibition ofMT1 is a bivalent chemical probe of BET bromodomains, with an IC50 of 0. 789 nM for BRD4(1). Product information CAS Number: 2060573 82 0 Molecular Weight: 1134. 20 Formula: C54H66Cl2N10O9S2 Chemical Name: 2 [(9S) 7 (4 chlorophenyl) 4,5,13 trimethyl 3 thia 1,8,11,12 tetraazatricyclo[8. 3. 0. 0,]trideca 2(6),4,7,10,12 pentaen 9 yl] N (23 {2 [(9S) 7 (4 chlorophenyl) 4,5,13 trimethyl 3 thia 1,8,11,12 tetraazatricyclo[8. 3. 0. 0,]trideca 2(6),4,7,10,12