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InChi: InChI=1S/C39H33Cl3N2O5S/c40-30-14-18-36-33(24-30)32(20-22-49-31-15-12-29(13-16-31)39(45)46)37(19-21-43-50(47
I-BET151 was used at 10 µM final concentration in various in vitro assays
MK-0591 has a high affinity for 5-lipoxygenase activating protein (FLAP) as evidenced by an IC50 value of 1
Formula: C20H16N4O2S
InChi: InChI=1S/C23H34F3N5O7/c1-12(2)17(19(35)23(24
FTI 276 hydrochloride) InChi: InChI=1S/C39H33Cl3N2O5S/c40-30-14-18-36-33(24-30)32(20-22-49-31-15-12-29(13-16-31)39(45)46)37(19-21-43-50(47FTI 276 is a protein farnesyl transferase (PFT) inhibitor with IC50s of 0. 9 and 0. 5 nM for Plasmodium falciparum and human. Product information CAS Number: 170006 72 1 Molecular Weight: 433. 59 Formula: C21H27N3O3S2 Chemical Name: (2S) 2 [(5 {[(2R) 2 amino 3 sulfanylpropyl]amino} [1,1' biphenyl] 2 yl)formamido] 4 (methylsulfanyl)butanoic acid Smiles: CSCC[C@H](NC(=O)C1=CC=C(C=C1C1C=CC=CC=1)NC[C@@H](N)CS)C(O)=O InChiKey: ZIXDDEATQSBHHL BEFAXECRSA N