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CE-245677 is a potent reversible inhibitor of Tie2 and TrkA/B kinases with a cellular IC50 of 4
The bioavailability in high dose experiments (>10 mg/kg) is always above 50% in mice
15-18H2/b24-23-
GW4064 could reduce induction of proinflammatory cytokines by LPS in vitro
InChiKey: AWHLTHOHBAGPMY-UHFFFAOYSA-N
Methyltetrazine-PEG8-NHS ester Catalog No.:M32200-C CE-245677 is a potent reversibleMethyltetrazine PEG8 NHS ester is a PEG based PROTAC linker that can be used in the synthesis of PROTACs. Product information CAS Number: 2183440 34 6 Molecular Weight: 709. 74 Formula: C32H47N5O13 Chemical Name: 2,5 dioxopyrrolidin 1 yl 1 [4 (6 methyl 1,2,4,5 tetrazin 3 yl)phenoxy] 3,6,9,12,15,18,21,24 octaoxaheptacosan 27 oate Smiles: CC1N=NC(=NN=1)C1C=CC(=CC=1)OCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)ON1C(=O)CCC1=O InChiKey: HBEBYIRKMRTDSK UHFFFAOYSA N
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