PLX-4720 - CAS# 918505-84-7 60209 90% PEG300

90% PEG300

but activates only the α7 to any significant extent

Epigenetics

Pustovit K

potent and selective G-protein coupled receptor kinase 2 and 3 (GRK2/GRK3) inhibitor (IC50 values are 35 and 32 nM at GRK2 and GRK3 respectively)

PLX-4720 - CAS# 918505-84-7 60209 90% PEG300PLX 4720, CAS No. 918505 84 7, is a 7 azaindole derivative that inhibits B Raf(V600E) with an IC(50) of 13 nM, defines a class of kinase inhibitor with marked selectivity in both biochemical and cellular assays. PLX 4720 preferentially inhibits the active B Raf(V600E) kinase compared with a broad spectrum of other kinases, and potent cytotoxic effects are also exclusive to cells bearing the V600E allele. Product information CAS Number: 918505 84 7