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Solubility: DMSO : 100 mg/mL (265
InChi: InChI=1S/C23H28O7/c1-11-7-13-8-16-21(30-10-29-16)22(27-5)17(13)18-14(19(24)12(11)2)9-15(25-3)20(26-4)23(18)28-6/h8-9
InChiKey: SLJKKTFIAUAYGR-UHFFFAOYSA-N
are greatly diminished in Baricitinib treated mice compare with vehicle control treated mice
It inhibits metastasis in an MHCC97-H mouse xenograft model but does not reduce tumor growth
TAK-828F strel Solubility: DMSO : 100 mg/mLTAK 828F is a potent, selective, and orally available retinoic acid receptor related orphan receptor t (RORt) inverse agonist (binding IC50=1. 9 nM, reporter gene IC50=6. 1 nM). TAK 828F shows excellent RORt isoforms selectivity (>5000 fold selectivity against human ROR and ROR). Product information CAS Number: 1854901 94 2 Molecular Weight: 509. 57 Formula: C28H32FN3O5 Chemical Name: 2 {3 [(5R) 5 [(7 fluoro 1,1 dimethyl 2,3 dihydro 1H inden 5