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5-oxadiazol-3-yl)-1-ethyl-1H-imidazo[4
Formula: C16H15N3O2
∼50 and ∼50 nM for PARP1
Ro 31-8220 mesylate
at concentrations 5- to 10-fold higher than the MIC required to kill planktonically growing fungal pathogens
TX1-85-1 cium) 5-oxadiazol-3-yl)-1-ethyl-1H-imidazo[4TX1 85 1 is an irreversible Her3 (ErbB3) inhibitor with an IC50 of 23 nM. TX1 85 1 is also the first selective Her3 ligand, which forms a covalent bond with Cys721 located in the ATP binding site of Her3. TX1 85 1 induces partial degradation of Her3 protein and attenuates Her3 dependent signaling. Product information CAS Number: 1603845 32 4 Molecular Weight: 580. 68 Formula: C32H36N8O3 Chemical Name: N (5 {1 [4 (4 acetylpiperazin 1 yl)cyclohexyl] 4
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