IPA-3 Size:2mg solid 8-difluoro-1-(2-fluoroethyl)-7-(4-methylpiperazin-1-yl)-4-oxo-1

8-difluoro-1-(2-fluoroethyl)-7-(4-methylpiperazin-1-yl)-4-oxo-1

Chemical Name: 2-{4-[(4S

Chemical Name: sodium 5-amino-1

and inhibits arachidonic acid conversion into the thromboxane-2 and prostaglandin-2 families

1218942-37-0

IPA-3 Size:2mg solid 8-difluoro-1-(2-fluoroethyl)-7-(4-methylpiperazin-1-yl)-4-oxo-1IPA 3 is a potent and selective PAK1 inhibitor. IPA 3 inhibits the growth of liver cancer cells by suppressing PAK1 and NF B activation. IPA 3 treatment significantly inhibited the growth of HCC cells. The mechanisms through which IPA 3 treatment suppresses HCC cell growth are enhancement of apoptosis and blockage of activation of NF B. IPA 3 not only inhibits the HCC cell growth, but also suppresses the metastatic potential of HCC cells. Nude mouse