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Formula: C22H20N4OS2
IP administration of I-BET151 at 30 mg/kg once per day was shown to provide survival benefit in two distinct mouse models of murine MLL–AF9 and human MLL–AF4 leukaemia
is highly potent and selective mutant JAK2 (V617F) inhibitor with an IC50 of ~55 nM
which is nontoxic to cells per se
and cell-permeable small-molecule agonist of the Hedgehog pathway
N3-tri-EG-OSu - CAS# 1245718-89-1 Catalog No.:L60004 Formula: C22H20N4OS2N3 tri EG OSu, CAS No. 1245718 89 1, is a PEG derivative containing an azide group and an NHS ester. The hydrophilic PEG spacer increases solubility in aqueous media. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The NHS ester can be used to label the primary amines ( NH2) of proteins, amine modified oligonucleotides, and other amine containing molecules. Product information CAS Number:
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