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a mitotic Kinesin Eg5 inhibitor
Formula: C20H16Cl2N4
PPQ-102 is a potent and voltage-independent CFTR inhibitor which completely inhibit CFTR chloride current with IC50 approximately 90 nM
When exposed to specific wavelengths of light
including T315I
Torcetrapib 02895 Hydrochloride a mitotic Kinesin Eg5 inhibitorTorcetrapib, also known as CP 529,414 was a drug being developed to treat hypercholesterolemia (elevated cholesterol levels) and prevent cardiovascular disease. Its development was halted in 2006 when phase III studies showed excessive all cause mortality in the treatment group receiving a combination of atorvastatin (Lipitor) and torcetrapib. Torcetrapib acts (as a CETP inhibitor) by inhibiting cholesterylester transfer protein (CETP), which normally