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1039/b912395b
Chemical Name: 6H-Thieno[3
Molecular Pathways: Endothelial Cell FAK-A Target for Cancer Treatment
(2013) Cancer Med
Smiles: CC(C)(C)C1NC2=C(N=1)C1C=CNC(=O)C=1C1=CC(F)=CC=C12
GSK-923295 - CAS# 1088965-37-0 size:2mg solid 1039/b912395bGSK 923295, CAS No. 1088965 37 0, also known as GSK 923295A, is a novel antimitotic inhibitor of centromere associated protein E (CENP E) with potential anticancer activity. GSK 923295A demonstrated significant antitumor activity against solid tumor models, inducing CRs in Ewing sarcoma, rhabdoid, and rhabdomyosarcoma xenografts. Clinical study showed that GSK 923295 had dose proportional pharmacokinetics and a low number of grade 3 or 4 adverse
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