Pay in 4 interest-free payments of $25.00 Learn more
Ships within 48 hours · Estimated delivery Aug 2 - Aug 7
selective and cell-permeable p300/CBP histone acetyltransferase (HAT) inhibitor with an IC50 ~400 nM
It blocks sGC activity in murine cerebellum induced by S-nitroso-glutathione and NMDA (IC50 values are 17 and 20 nM respectively)
reducing capabilities and Fe2+ chelating effects
PR-104A is metabolized under hypoxia by the 1-electron NADPH:cytochrome P450 oxidoreductase
CALP3 causes dose-dependent inhibition of apoptosis (IC50=33
TAK-659 3992 selective and cell-permeable p300/CBP histoneTAK 659 is a highly potent, selective, reversible and orally available dual inhibitor of spleen tyrosine kinase (SYK) and fms related tyrosine kinase 3 (FLT3), with an IC50 of 3. 2 nM and 4. 6 nM for SYK and FLT3, respectively. TAK 659 induces cell death in tumor cells but not in nontumor cells, and with potential for the treatment of chronic lymphocytic leukemia (CLL). Product information CAS Number: 1312691 33 0 Molecular Weight: 344. 39 Formula:
US$ 30.00
US$ 75.00
US$ 60.00
US$ 35.00