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129(8):3121-3133
Emixustat potently inhibits isomerase activity in vitro (IC50=4
a dose-dependent increase in p16expression is observed with Guadecitabine sodium (SGI-110 sodium)
Formula: C30H37ClN8O4
InChi: InChI=1S/C23H32O3/c1-3-4-5-22(25)26-21-11-10-20-19-8-6-15-14-16(24)7-9-17(15)18(19)12-13-23(20
ML786 dihydrochloride Catalog No.:M19993-C 129(8):3121-3133ML786 dihydrochloride is a potent and orally bioavailable Raf inhibitor, with IC50s of 2. 1, 4. 2, and 2. 5 nM for V600EB Raf, wt B Raf, and C Raf, respectively. ML786 dihydrochloride also inhibits Abl 1, DDR2, EPHA2, KDR, and RET (IC50=<0. 5, 7. 0, 11, 6. 2, 0. 8 nM). ML786 dihydrochloride can be used for the research of cancers. Product information CAS Number: 1237536 18 3 Molecular Weight: 611. 48 Formula: C29H31Cl2F3N4O3 Chemical Name: (Z) 3 (2