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TW-37 induces cell growth inhibition and S-phase cell cycle arrest
EMD-638683
Treatment with BX471
CH4O3S/c1-15-18(23(29)28-10-3-2-4-21(28)25-15)9-13-27-11-7-16(8-12-27)22-19-6-5-17(24)14-20(19)30-26-22
Oprea1_287445
Sildenafil Catalog No.:M10317-10 TW-37 induces cell growth inhibitionSildenafil is a selective inhibitor of PDE5 (type 5 cGMP phosphodiesterase) which catalyzes the hydrolysis of 3',5' cyclic guanosine monophosphate (cGMP). As a PDE5 inhibitor, Sildenafil has been reported to enhance neuro , synapto and angiogenesis in rat models of stroke and also is reported to be a mild vasodilator. Sildenafil has also been shown to prevent indomethacin induced small intestinal ulceration formation through an NO cGMP dependent
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