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Nomifensine-d3 maleate - CAS# 1795140-41-8 14625 Giovannini M

SKU: 6276058894

4.3
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Description

Giovannini M

2-9H3/t21-

Formula: C20H20N6O3

Smiles: CC1=NC=C(N1CCC1C=CN=CC=1)[N+]([O-])=O

Smiles: CC(C)(C)[Si](C)(C)O[C@@H]1[C@H](O)[C@@H](COC(C2C=CC=CC=2)(C2C=CC(=CC=2)OC)C2C=CC(=CC=2)OC)O[C@H]1N1C=NC2C(NC(=O)C3C=CC=CC=3)=NC=NC1=2

Nomifensine-d3 maleate - CAS# 1795140-41-8 14625 Giovannini MNomifensine d3 (() Nomifensine d3) maleate is the deuterium labeled Nomifensine maleate (HY B1110A). Nomifensine (() Nomifensine) is a potent norepinephrine (NE) and dopamine (DA) reuptake inhibitor. Nomifensine inhibits uptake of NE, DA and 5 HT in rat brain synaptosomes, with IC50 values of 6. 6 nM, 48 nM and 830 nM, and Ki values of 4. 7 nM, 26 nM and 4000 nM, respectively. Nomifensine shows low or ineffective binding activity to dopamine D2, 1

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