Pay in 4 interest-free payments of $22.25 Learn more
Ships within 48 hours · Estimated delivery Aug 5 - Aug 10
960374-59-8
It inhibits LSD1 in biochemical assay with an IC50 ~16 nM
ATB-346 may therefore be an attractive agent for chemoprevention of colon cancer
18(20):2069-2078
PubMed Central PMCID: PMC4275380
GSK-LSD1 - LSD1 Inhibitor. CAS# 2102933-95-7 0073 960374-59-8GSK LSD1, CAS No. 2102933 95 7, is a highly potent, specific and irreversible inhibitor of Lysine Specific Demethylase 1 (LSD1). It inhibits LSD1 in biochemical assay with an IC50 ~16 nM, and is > 1000 fold selective over other closely related FAD utilizing enzymes (i. e. LSD2, MAO A, MAO B). GSK LSD1 induces gene expression changes in cancer cell lines (average EC50 < 5 nM) and inhibits cancer cell line growth (average EC50 < 5 nM). Product
US$ 14.95
US$ 62.95
US$ 19.95
US$ 148.50
US$ 81.00
US$ 78.00
US$ 14.99