GJ072 is active in A-T cells with a homozygous TAA mutation
InChi: InChI=1S/C17H13NO2/c19-16-10-9-12-5-1-2-6-13(12)14(16)11-18-15-7-3-4-8-17(15)20/h1-11
Chemical Name: N-methyl-N-(3-(((2-((2-oxoindolin-5-yl)amino)-5-(trifluoromethyl)pyrimidin-4-yl)amino)methyl)pyridin-2-yl)methanesulfonamide
RKI-1447 is also highly selective at inhibiting ROCK-mediated cytoskeleton re-organization
Epub 2019 Aug 1
10-Oxo Docetaxel 60094 GJ072 is active in A-T10 Oxo Docetaxel (Docetaxel Impurity 1) is a novel taxoid having remarkable anti tumor properties and a Docetaxel intermediate. Product information CAS Number: 167074 97 7 Molecular Weight: 805. 86 Formula: C43H51NO14 Chemical Name: (1S,2S,3R,4S,7R,9S,10S,15S) 4 (acetyloxy) 15 {[(2R,3S) 3 {[(tert butoxy)carbonyl]amino} 2 hydroxy 3 phenylpropanoyl]oxy} 1,9 dihydroxy 10,14,17,17 tetramethyl 11,12 dioxo 6 oxatetracyclo[11. 3. 1. 0,. 0,]heptadec 13 en 2