(S)-3-((1-methylpyrrolidin-2-yl)methyl)-5-(2-(phenylsulfonyl)ethyl)-1H-indole-d3 n IX Chemical Name: {6-[2-({5-[(4-ethylpiperazin-1-yl)methyl]pyridin-2-yl}amino)-5-fluoropyrimidin-4-yl]-4-fluoro-1-(propan-2-yl)-1H-1

Chemical Name: {6-[2-({5-[(4-ethylpiperazin-1-yl)methyl]pyridin-2-yl}amino)-5-fluoropyrimidin-4-yl]-4-fluoro-1-(propan-2-yl)-1H-1

Smiles: OC(=O)C1C=CC=CC=1S(=O)(=O)NCCCCN1C(=O)C2=CC=CC3=CC=CC(=C32)C1=O

MISO pretreatment could result in a greater amount of binding of MEL to DNA at early times after injection

BT18 (5-50 μM

4Na/c48-37(42-27-1-9-33(10-2-27)65(53

(S)-3-((1-methylpyrrolidin-2-yl)methyl)-5-(2-(phenylsulfonyl)ethyl)-1H-indole-d3 n IX Chemical Name: {6-[2-({5-[(4-ethylpiperazin-1-yl)methyl]pyridin-2-yl}amino)-5-fluoropyrimidin-4-yl]-4-fluoro-1-(propan-2-yl)-1H-1Product information CAS Number: 1217698 26 4 Molecular Weight: 385. 54 Formula: C22H26N2O2S Chemical Name: 5 [2 (benzenesulfonyl)ethyl] 3 {[(2S) 1 (H)methylpyrrolidin 2 yl]methyl} 1H indole Smiles: [2H]C([2H])([2H])N1CCC[C@H]1CC1=CNC2=CC=C(CCS(=O)(=O)C3C=CC=CC=3)C=C12 InChiKey: PWVXXGRKLHYWKM COJYBMMNSA N InChi: InChI=1S C22H26N2O2S c1 24 12 5 6 19(24)15 18 16 23 22 10 9 17(14 21(18)22)11 13 27(25,26)20 7 3 2 4 8 20 h2 4,7 10,14,16,19,23H,5 6,11