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CCF-642 - CAS# 346640-08-2 size:2mg solid Chemical Name: Bleomycin sulfate

SKU: 70914792292

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Description

Chemical Name: Bleomycin sulfate

Neurodazine

Phase I Study of the JAK2 V617F Inhibitor

Incubation of the malignant lymphocytes with Salinomycin induces apoptosis within 48 h

CAS Number: 2622-24-4

CCF-642 - CAS# 346640-08-2 size:2mg solid Chemical Name: Bleomycin sulfateCCF 642, CAS No. 346640 08 2, is a protein disulfide isomerase (PDI) inhibitor. CCF642 exhibited a submicromolar IC50 in 10 of 10 multiple myeloma cell lines. In vitro, CCF642 inhibited PDI reductase activity about 100 fold more potently than the structurally distinct established inhibitors PACMA 31 and LOC14. CCF642 displayed potent efficacy in an aggressive syngeneic mouse model of multiple myeloma and prolonged the lifespan of C57BL KaLwRij mice

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