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ZINC26377671
Crenolanib (10 mg/kg and 20 mg/kg) suppresses non-small-cell lung cancer tumor growth in vivo and induces tumor cell apoptosis
consistent with clinical data for other NK1 antagonists
TAK-779 did not affect production of IL-12 by antigen-presenting cells
PI3K inhibitor BEZ235 specifically inhibits PIK3 in the PI3K/AKT kinase (or protein kinase B) signaling pathway
HOKU-81 egabalin ZINC26377671Hoku 81 is a bronchodilator, and one of the metabolites of tulobuterol. HOKU 81 was approximately 8 times more potent than tulobuterol, approximately twice as potent as salbutamol, and approximately as potent as isoprenaline in relaxing effect on the isolated tracheal smooth muscle preparation of guinea pigs. Product information CAS Number: 58020 43 2 Molecular Weight: 243. 73 Formula: C12H18ClNO2 Chemical Name: 4 [2 (tert butylamino) 1 hydroxyethyl]