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BMSpep-57 inhibits PD-1/PD-L1 binding up to 98
not by inflammasome activation
113 nM) and H3-receptors (Ki = 12
CYP1A1/2 CYP2B1/2
In a murine MPN model
PF-04418948 Size:Contact [email protected] for quotation BMSpep-57 inhibits PD-1/PD-L1 binding upPF 04418948 is an orally active, potent and selective prostaglandin EP2 receptor antagonist with an IC50 of 16 nM. Product information CAS Number: 1078166 57 0 Molecular Weight: 409. 41 Formula: C23H20FNO5 Chemical Name: 1 (4 fluorobenzoyl) 3 {[(6 methoxynaphthalen 2 yl)oxy]methyl}azetidine 3 carboxylic acid Smiles: COC1=CC2C=CC(=CC=2C=C1)OCC1(CN(C1)C(=O)C1C=CC(F)=CC=1)C(O)=O InChiKey: LWJGMYMNSNVCEM UHFFFAOYSA N InChi: InChI=1S C23H20FNO5 c1 29 19 8
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