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TAK-960 hydrochloride (8 nM) leads to G2/M cell cycle arrest without significant cytotoxicity in HeLa cells
Smiles: CC(C)=CCC1=C2OC=C(C(=O)C2=C(O)C=C1O)C1C=CC(O)=CC=1
BW 245C (100 nM) does not significantly increase MBP-positive eosinophils in esophageal epithelium in OVA-sensitized guinea pigs
Incorporation of OABK (0
on a par with vemurafenib IC50 values in the same assays (0
m-PEG3-Sulfone-PEG4-propargyl 1082 TAK-960 hydrochloride (8 nM) leadsm PEG3 Sulfone PEG4 propargyl is a PEG based PROTAC linker that can be used in the synthesis of PROTACs. Product information CAS Number: 2055041 02 4 Molecular Weight: 426. 52 Formula: C18H34O9S Chemical Name: 1 {2 [2 (2 methoxyethoxy)ethoxy]ethanesulfonyl} 3,6,9,12 tetraoxapentadec 14 yne Smiles: COCCOCCOCCS(=O)(=O)CCOCCOCCOCCOCC#C InChiKey: RZOCFVBQMWCPJD UHFFFAOYSA N InChi: InChI=1S C18H34O9S c1 3 4 22 7 8 24 9 10 25 12 14 27 16 18 28(19,20)17 15
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