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with an IC50 of ~50 nM with either substrate
the IC50 of ZT-12-037-01 against STK19 accordingly increased
Woodrow MD
2012 Aug 15
Formula: C50H62ClN9O8S2
Mesna Size:Solid 2 mg with an IC50 of ~50Mesna is a sulfhydryl compound that is used to reduce the incidence of hemorrhagic cystitis associated with certain chemotherapeutic agents. Mesna is converted to a free thiol compound in the kidney, where it binds to and inactivates acrolein and other urotoxic metabolites of ifosfamide and cyclophosphamide, thereby reducing their toxic effects on the urinary tract during urinary excretion. Check for active clinical trials or closed clinical trials
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