RORγt agonist 1 Catalog No.:M30089-C Smiles: CC(=O)NCCC1C2=CC=CC=C2NC=1CC1C=CC=CC=1

Smiles: CC(=O)NCCC1C2=CC=CC=C2NC=1CC1C=CC=CC=1

Neither body weight nor the weight of any organ tested is affected by CGP-53153

IPI-9119 is an orally active

A selective TSH receptor antagonist inhibits stimulation of thyroid function in female mice

but does not affect phosphorylation of ER alpha at Ser (118)

RORγt agonist 1 Catalog No.:M30089-C Smiles: CC(=O)NCCC1C2=CC=CC=C2NC=1CC1C=CC=CC=1RORt agonist 1 (compound 14) is a potent, orally bioavailable RORt agonist with an EC50 of 20. 8 nM. RORt agonist 1 showes high metabolic stability, improved aqueous solubility and excellent mouse PK profile. RORt agonist 1 is a potential candidate of RORt agonist for cancer immunotherapy. Product information CAS Number: 2377378 89 5 Molecular Weight: 545. 45 Formula: C24H17F6NO5S Chemical Name: 2 {6 [3 (difluoromethoxy) 5 fluorophenyl] 1 [3