cis-4-Hydroxy-L-proline Catalog No.:M16561-C Smiles: CN1C=NC2=C1C(=O)N(CCCN1C(=O)N(C)C3N=CN(C)C=3C1=O)C(=O)N2C

Smiles: CN1C=NC2=C1C(=O)N(CCCN1C(=O)N(C)C3N=CN(C)C=3C1=O)C(=O)N2C

ONO-9780307 is used to solve the LPA1 crystal structure

and result in overproduction of the (R)-enantiomer of 2- hydroxyglutarate [(R)-2-HG]

It also specifically inhibited kinase activity of the protein (IC50 = 370+/-120 pM)

The expression of LC3B-II is a good marker for autophagosome formation in the autophagy process

cis-4-Hydroxy-L-proline Catalog No.:M16561-C Smiles: CN1C=NC2=C1C(=O)N(CCCN1C(=O)N(C)C3N=CN(C)C=3C1=O)C(=O)N2Ccis 4 Hydroxy L proline, a proline analogue, is an inhibitor of collagen production. cis 4 Hydroxy L proline could inhibit fibroblast growth by preventing the deposition of triple helical collagen on the cell layer. cis 4 Hydroxy L proline also depresses the growth of primary N nitrosomethylurea induced rat mammary tumors. Product information CAS Number: 618 27 9 Molecular Weight: 131. 13 Formula: C5H9NO3 Chemical Name: (2S,4S) 4 hydroxypyrrolidine 2