Amlexanox - CAS# 68302-57-8 Size:100 mg solid 54(4):352-4

54(4):352-4

a potent and specific inhibitor of the tyrosine kinase activity of receptors for the EGF family of growth factors

is a highly potent and orally active transforming acidic coiled-coil 3 (TACC3) inhibitor with an IC50 of 188 nM and a Kd of 1

Formula: C21H20N2O2

473(2):265-8

Amlexanox - CAS# 68302-57-8 Size:100 mg solid 54(4):352-4Amlexanox, also known as AA 673 and CHX 3673, is an anti inflammatory antiallergic immunomodulator used to treat recurrent aphthous ulcers (canker sores), and (in Japan) several inflammatory conditions. Amlexanox inhibits the synthesis and release of inflammatory mediators, including leukotrienes and histamine, from mast cells, neutrophils, and mononuclear cells. Amlexanox also acts as a leukotriene D4 antagonist and a phosphodiesterase inhibitor.