Hydroxy-Dynasore Catalog No.:M25683-C Smiles: NC(=O)C1=CN=C(NCCC2=CC(Cl)=C(O)C=C2)N=C1NCC1C=CC=CC=1

Smiles: NC(=O)C1=CN=C(NCCC2=CC(Cl)=C(O)C=C2)N=C1NCC1C=CC=CC=1

CAS Number: 102146-07-6

InChi: InChI=1S/C25H31F3N4O2/c1-32(2)13-12-29-24(33)30-15-18-9-10-19-22(16-6-4-3-5-7-16)31-21-11-8-17(25(26

Chemical Name: 2-cyclopropyl-5-[1-(2-fluoropyridin-3-yl)-5-methyl-1H-1

decreasing enzymatic activity with an apparent Ki of 0

Hydroxy-Dynasore Catalog No.:M25683-C Smiles: NC(=O)C1=CN=C(NCCC2=CC(Cl)=C(O)C=C2)N=C1NCC1C=CC=CC=1Hydroxy Dynasore (Dyngo 4a), a structural analog of Dynasore (HY 15304), is an potency improved, low cytotoxicity and nonspecific binding dynamin inhibitor with IC50 values of 0. 38 M and 2. 3 M for brain dynamin I and recombinant rat dynamin II, respectively. Hydroxy Dynasore inhibits dynamindependent endocytosis of transferrin with an IC50 of 5. 7 M in vitro. Product information CAS Number: 1256493 34 1 Molecular Weight: 338. 31 Formula: C18H14N2O5