Fedratinib hydrochloride hydrate ((2S)-1 2-propanediol hydrate) Smiles: C[C@H]1C=C(C[C@H](O)CCCCC[C@@H](O)CCCC[C@@H](O)[C@H]2CC[C@@H](O2)[C@H](O)CCCCCCCCCCCC)C(=O)O1

Smiles: C[C@H]1C=C(C[C@H](O)CCCCC[C@@H](O)CCCC[C@@H](O)[C@H]2CC[C@@H](O2)[C@H](O)CCCCCCCCCCCC)C(=O)O1

InChiKey: LJBQRRQTZUJWRC-UHFFFAOYSA-N

HS-173 induced cell cycle arrest at the G(2)/M phase and apoptosis

Structural and mechanistic insights into nuclear transport and delivery of the critical pluripotency factor Oct4 to DNA

InChi: InChI=1S/C22H22N2O4/c1-15-14-16(2)24-21(23-15)28-19(20(25)26)22(27-3

Fedratinib hydrochloride hydrate ((2S)-1 2-propanediol hydrate) Smiles: C[C@H]1C=C(C[C@H](O)CCCCC[C@@H](O)CCCC[C@@H](O)[C@H]2CC[C@@H](O2)[C@H](O)CCCCCCCCCCCC)C(=O)O1Fedratinib hydrochloride hydrate (TG 101348 hydrochloride hydrate) is a potent, selective, ATP competitive and orally active JAK2 inhibitor with IC50s of 3 nM for both JAK2 and JAK2V617F kinase. Fedratinib hydrochloride hydrate shows 35 and 334 fold selectivity over JAK1 and JAK3, respectively. Fedratinib hydrochloride hydrate induces cancer cell apoptosis and has the potential for myeloproliferative disorders research. Product information CAS Number: