Mavacamten ative whereas SBE7-β-CD exhibits strong solubilizing

whereas SBE7-β-CD exhibits strong solubilizing effects over a wide concentration range

25)/t10-/m0/s1

AR7 was suggested to be used at 5-20 µM final concentration in vitro and in cellular assays

CBP/EP300-IN-2

Smiles: [2H][13C]([2H])([2H])[C@]1(F)[C@@H](O[C@H](CO)[C@H]1O)N1C=CC(=O)NC1=O

Mavacamten ative whereas SBE7-β-CD exhibits strong solubilizingMavacamten (MYK461) is an orally active modulator of cardiac myosin, with IC50s of 490, 711 nM for bovine cardiac and human cardiac, respectively. Product information CAS Number: 1642288 47 8 Molecular Weight: 273. 33 Formula: C15H19N3O2 Chemical Name: 6 {[(1S) 1 phenylethyl]amino} 3 (propan 2 yl) 1,2,3,4 tetrahydropyrimidine 2,4 dione Smiles: CC(C)N1C(=O)NC(=CC1=O)N[C@@H](C)C1C=CC=CC=1 InChiKey: RLCLASQCAPXVLM NSHDSACASA N InChi: InChI=1S C15H19N3O2