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Galeterone (TOK-001) is both a CYP17A1 inhibitor and androgen receptor antagonist and the similarity of these binding modes is likely the reason for this dual mechanism of action
Discovery of orally active carboxylic acid derivatives of 2-phenyl-5-trifluoromethyloxazole-4-carboxamide as potent diacylglycerol acyltransferase-1 inhibitors for the potential treatment of obesity and diabetes
Mer receptor tyrosine kinase is ectopically expressed in ALL patient samples and cell lines
Overexpression of CRBN wild-type protein
147591-46-6
DOTA derivative Size:Solid 2 mg Galeterone (TOK-001) is both aDOTA derivative is a benxyl derivative of the cyclic tosamide; can be nitrated directly; is more convenient to incorporate the nitro group after deprotection lithium aluminum hydride. Product information CAS Number: 153777 70 9 Molecular Weight: 879. 14 Formula: C43H50N4O8S4 Chemical Name: 2 benzyl 1,4,7,10 tetrakis(4 methylbenzenesulfonyl) 1,4,7,10 tetraazacyclododecane Smiles:
US$ 169435.00
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