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IC50 values for all other kinases are in the μM range (FYN
February 1966
Displays some inhibitory activity towards c-Kit
JTK-853 induces apparent Huh-7
Theliatinib (2-15 mg/kg
G5-7 tanediol IC50 values for all otherG5 7, an orally active and allosteric JAK2 inhibitor, selectively inhibits JAK2 mediated phosphorylation and activation of EGFR (Tyr1068) and STAT3 by binding to JAK2. G5 7 induces cell cycle arrest, apoptosis and possesses antiangiogenic effect. G5 7 has the potential for glioma study. Product information CAS Number: 939681 36 4 Molecular Weight: 411. 44 Formula: C24H23F2NO3 Chemical Name: tert butyl (3Z,5Z) 3,5 bis[(2 fluorophenyl)methylidene] 4