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Fingolimod hydrochloride 7903 67(2):83-92

SKU: 93891309679

4.4
USD96.00 USD136.00

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Description

67(2):83-92

GW3965 hydrochloride up-regulates expression of the cholesterol transporter gene ABCA1 and the E3 ubiquitin ligase IDOL and reduces LDLR levels

(-)-Huperzine A significantly inhibits AChE activity in the cortex

Trimethylamine N-oxide (TMAO) contributes to cardiovascular diseases by promoting inflammatory responses

2(6):799-803

Fingolimod hydrochloride 7903 67(2):83-92Fingolimod hydrochloride (FTY720), an analog of sphingosine, is a potent sphingosine 1 phosphate (S1P) receptors modulator. Fingolimod hydrochloride is phosphorylated by sphingosine kinases, particularly by SK2, and then binds S1PR1, 3, 4, and 5. Fingolimod hydrochloride induces the internalization of S1P1, and consequently, inhibits S1P activity. Fingolimod hydrochloride also is a pak1 activator Product information CAS Number: 162359 56 0 Molecular

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